Can the RTX 6000D run Qwen2.5 72B?
Yes. Qwen2.5 72B fits the RTX 6000D's 84 GB at Q4_K_M (about 41.8 GB needed), running at an estimated 23 tok/s. There's room for up to Q8_0 if you want higher quality.
Every quantization
Qwen2.5 72B (72B) on 84 GB
| Quant | Weights | Needs | Fit | Est. speed |
|---|---|---|---|---|
| Q4_K_M | 40 GB | 41.8 GB | Fits easily | ~23 tok/s |
| Q5_K_M | 48 GB | 49.8 GB | Fits easily | ~19 tok/s |
| Q8_0 | 78 GB | 79.8 GB | Tight | ~12 tok/s |
| FP16 | 144 GB | 145.8 GB | Too big | - |
Estimates. Needs = weights + 1.8 GB for KV cache and runtime at modest context. Speed is single-stream decode scaled from the RTX 6000D's 1570 GB/s bandwidth (Estimated from memory bandwidth (llama.cpp decode)). Long contexts need more memory and run slower.
Run it
Copy, paste, go
ollama run qwen2.5:72bllama-server -hf Qwen/Qwen2.5-72B-Instruct-GGUF -ngl 99Ollama pulls a Q4 build by default. Pick a larger quant only if the table above says it fits. Full Qwen2.5 72B details →
Compare
Same model, other hardware - and other models on this card
Qwen2.5 72B on other hardware
- MacBook Pro 16" M4 Max~7.8 tok/s
- DGX Spark (GB10)~3.9 tok/s
- RTX Spark N1X (128 GB)~3.9 tok/s
Also runs on the RTX 6000D
- Llama 3.3 70B~23 tok/s
- Qwen3.6 35B A3B~343 tok/s
- Qwen3.5 35B A3B~343 tok/s
- dolphin-2.9.1-yi-1.5-34b~45 tok/s
- Gemma 4 31B~47 tok/s
- Qwen3 32B~47 tok/s
- GLM-4.7-Flash~347 tok/s
- Qwen3-30B-A3B-Instruct-2507~339 tok/s
Frequently asked
Quick answers
Can the RTX 6000D run Qwen2.5 72B?
Yes. Qwen2.5 72B fits the RTX 6000D's 84 GB at Q4_K_M (about 41.8 GB needed), running at an estimated 23 tok/s. There's room for up to Q8_0 if you want higher quality.
How much VRAM does Qwen2.5 72B need?
About 40 GB of weights at Q4_K_M, 78 GB at Q8_0 and 144 GB at FP16. Add roughly 1.8 GB for the KV cache and runtime at modest context lengths.
How fast is Qwen2.5 72B on the RTX 6000D?
Roughly 23 tokens per second at Q4_K_M (single user, llama.cpp-style decode). This is an estimate from the RTX 6000D's 1570 GB/s memory bandwidth.